Thank you for requesting your test!

Your Oral Health Test will arrive at your house in 3-4 business days.

"Our understanding of the importance of pathogenic microbes to oral health is important because the three main oral diseases—dental caries, periodontitis, and oropharyngeal cancer—begin with an underlying microbial dependence."

Vice Admiral Vivek H. Murthy, MD, MBA
U.S. Surgeon General

Identify and address the root cause of oral conditions

Oral health is rooted in your oral microbiome. Our at-home test measures 700+ bacteria, fungi and viruses in your saliva to detect issues early before they become problems.  

3 simple steps for better oral health


Order your test - we'll deliver it directly to you in 2-3 days.


Send your saliva sample to our lab in a prepaid envelope.


Get your oral health report card & action plan in two weeks.

Good health starts with a healthy mouth

The oral microbiome is the complex ecosystem of bacteria, fungi, and more that lives inside your mouth. Some keep our teeth and gums healthy, while others cause damage and cause conditions like bad breath, tooth decay and gum disease.

The latest research has also linked the oral microbiome to conditions like heart disease, Alzheimer’s and diabetes. 

Your oral microbiome is the foundation of your oral health. We help you identify and eliminate the harmful bacteria in your mouth to improve your oral and overall health.

Learn the science

  • As a biological dentist, Bristle has significantly enhanced our diagnostic capabilities, providing valuable insights beyond traditional assessments. My patients appreciate the detailed information, and I'm consistently impressed by the efficiency of the Bristle process and their excellent customer support. I highly recommend Bristle for any dental practice seeking to elevate patient care.

    Sharon Dickerson, DDS

  • Bristle is the future of oral health care. With a simple noninvasive saliva test, we can assess patients' periodontal and caries risk rather than just waiting for bone loss and decay. Why wait for a heart attack or stroke to treat cardiovascular diseases if you see elevated biomarkers in blood tests? The same should be true in the future for dental care.

    Jen Chiang, DDS

  • The Bristle test has shifted my treatment mindset from "kill mode" to "build and balance mode." Customizing patient treatment at a microbial level is the future of comprehensive dental care. Patients are becoming increasingly aware of the oral systemic connection and having a clear picture of their risk for disease helps us collaborate to create a pathway to health.

    Monica, RDH

  • It's like unlocking a key to a puzzle. The data is easy to understand an allows us to take a deep dive into the underlying root cause of issues that have confounded us in the past. Everything makes sense. Anyone who cares about their health and connecting the dots to the oral systemic connection needs to have the Bristle test done.

    Janet, RDH

  • No other salivary test is as comprehensive as Bristle. It allows me to share a broad view of positive and negative factors and dive deep when I need to. Detecting all microbes, including candida, is important for me to share with patients. I love that the report is provided to our office and to the patient. It has been very helpful to share with our patient's referring providers.

    Shannon, DDS and Janice, RDH

Functional dentists & hygienists love Bristle Health. Here's why.

Read about how offices are transforming the care they provide through oral microbiome testing.

Developed in collaboration with dental leaders

Dr. Mark Burhenne

Functional Dentist & Founder of

"The mouth is the gateway to your body and oral bacteria have been associated with a higher risk for systemic conditions including Alzheimer’s, diabetes, cardiovascular disease, and poor pregnancy outcomes. You can’t be healthy without a healthy mouth. And what you don’t measure, you cannot manage.”

  • Dr. Mark Burhenne, DDS

    Functional Dentist | Founder of

  • Kriston Reisnour RDH, BSDH, CCSH, CSOM, FAAOSH
    Dental Hygienist & Integrative Health Specialist

  • Dr. Jonathan Levine, DDS

    Prosthodontist, NYU Professor | Founder of GLO Science

  • Dr. Eric Pulver
    Oral Surgeon | Chief Dental Officer at Denti.Ai

  • Dr. Roshan Parikh, DDS

    General Dentist | President & CEO at Dntl Bar

Bristle Health White Paper

Explore our cutting-edge, affordable oral microbiome test to assess periodontal disease and dental caries risk.

Read More

The Oral-Gut Axis

The oral cavity is more than just an entry point to the digestive system. Explore the intricate relationship between oral and digestive health further!

Read More

Case Study: Serratia Marsecans

A patient with good oral hygiene and a healthy lifestyle faced recurring periodontal abscesses of unknown cause, alongside bleeding during cleanings and excessive interdental plaque.

Jen Chiang, DDS, used Bristle Health testing to identify the root-cause and restore this patient's oral health.

Download the case study